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Topaz Labs Photoshop Plugins Bundle 2015 (31.08.2015) [En] Keys
公開日:2023/01/14 / 最終更新日:2023/01/14
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Topaz Labs Photoshop Plugins Bundle 2015 (31.08.2015) [En] Keys
Topaz Labs Photoshop Plugins Bundle (31.08.2015) [En] Key For XTopaz Labs Photoshop Plugins Bundle (31.08.2015) [En].
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[Stimulation of the release of acetylcholine by ammonium ions in the rat hippocampus].
The effect of NH4+ on ACh release from hippocampal slices of rat was investigated by means of the stable labelling with [3H]choline (Ch) in vitro. Na+-H+ exchange was stimulated by NH4+, as it was shown by increase of the ratio of [3H]ACh (Ch-liberated) to [3H]choline (Ch-taken up). The Na+-H+ exchange rate was concentration dependent and it was much higher than that stimulated by Na+ in depolarized slices. K+-stimulated Ch-release was significantly augmented by NH4+ and the effect was concentration dependent. The release was also, but much less, increased by Ca2+ in depolarized slices. The interaction between NH4+ and K+ in stimulation of ACh release in depolarized slices of rat hippocampus was studied. NH4+ alone stimulated release of ACh while K+ inhibited it. The most effective K+ concentration was 1 mM, but the effect still persisted at 50 mM K+ and seemed to be nonspecific. NH4+ and K+ each provided an additive effect, but no effect was observed if NH4+ was added first. It is suggested that NH4+ directly stimulates K+-permeable channels in the plasma membrane and
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